The secret to intensely hydrated skin: boosting hyaluronic acid from within.

Hyaluronic acid is naturally present in the skin and plays a fundamental role in maintaining hydration, skin’s suppleness and volume. It acts like a molecular sponge, that attracts and retains water within the skin, ensuring comfort, firmness and radiance.

But over time, natural hyaluronic acid reserves decline. From the age of 25, hyaluronic acid levels gradually decrease, and environmental aggressors such as UV exposure, pollution and oxidative stress accelerate its degradation. The result? Dehydration lines become more visible, deeper wrinkles settle in, and the skin can appear dull and less resilient.

To restore a plump, smooth complexion, it is essential not only to replenish hyaluronic acid but also to stimulate its natural production and protect it from breakdown.

The Multi-Layer Approach to Long-Lasting Plumping

Hyaluronic acid works at different depths within the skin. For optimal wrinkle-filling performance, action is needed across multiple layers:

Surface level: to instantly hydrate and smooth dehydration lines.

Epidermal level: to visibly plump and reinforce the skin barrier.

Dermal level: to support structural hydration and help maintain skin density.

When hydration is restored at every level, the skin appears naturally fuller, smoother and more radiant.

What causes hyaluronic acid degradation?

Several internal and external factors contribute to hyaluronic acid loss:

Ageing: Natural cellular renewal slows, reducing synthesis.
Environmental stress: UV rays, pollution and free radicals accelerate degradation.
Lifestyle factors: Stress, lack of sleep and smoking can weaken the skin barrier and increase water loss.

Over time, all these causes compromises skin volume and accentuates visible signs of ageing.

Hyaluronic Acid + Polyglutamic Acid: A Synergistic Strategy

While topical hyaluronic acid replenishes moisture, advanced formulations can go further by stimulating natural production and limiting breakdown.

Polyglutamic acid enhances water retention and reinforces the action of hyaluronic acid, creating a powerful complex that maximises hydration longevity and visible plumping.

Institut Esthederm’s Intensive Hyaluronic+ Range

The Intensive Hyaluronic+ line is powered by Hyaluronic+ Patented Technology, an advanced complex combining three molecular weights of hyaluronic acid with polyglutamic acid to act throughout multiple skin layers.

Intensive Hyaluronic+ Range helps to:

Reactivate natural hyaluronic acid synthesis

Protect against hyaluronic acid degradation

Deliver immediate and long-lasting plumping

Smooth fine lines and deeper wrinkles

The range is also formulated with Cellular Water Technology, a 100% biomimetic water inspired by the skin’s own biological water. Rich in antioxidants, it optimises cellular energy, enhances radiance and supports skin longevity over time.

Clinically Proven Visible Results

Intensive Hyaluronic+ Serum*:

14% reduction in crow’s feet wrinkles

57% visible smoothing effect

*28 days, twice daily use, 33 women

Intensive Hyaluronic+ Cream* :

19% reduction in forehead wrinkles

21% plumping effect

*28 days, twice daily use, 31 women

A Targeted 2-Month Hydration Reset

For deep, multi-layer hydration and a powerful plumping effect with visibly reduced wrinkles, use the complete Intensive Hyaluronic+ routine:

Wrinkle-Filling Serum to deliver concentrated hydration, visibly smooth wrinkles and reactivate natural hyaluronic acid production.

Plumping Cream to lock in moisture, strengthen the skin barrier and provide lasting comfort while enhancing radiance.

Eye Contour Care to intensely hydrate and smooth the delicate eye area, visibly reducing dehydration lines and crow’s feet while restoring a refreshed, well-rested look.

Hydra-Plumping Mask to provide an instant moisture boost, replump the skin and boost luminosity, ideal as a weekly intensive treatment or whenever skin feels dehydrated and tight.

Used together as a targeted two-month routine, this complete routine restores optimal hydration levels, reinforces the skin’s natural plumping mechanisms and reveals smoother, fuller, more radiant-looking skin.

March 2, 2026